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Ignite Hope for Children Battling Rare Pediatric Cancers

Help us reach our goal to drive breakthroughs in treatments and bring comfort to all of the families in our community who are navigating unimaginable cancer challenges.

Every donation matters. Explore the best option for you.

Make a General Donation

Every dollar supports our mission to provide transformational outcomes for rare cancer heroes and their families across our region.

Your generous gift helps fund cutting-edge programs that make an actual difference in the rare pediatric cancer space.

Become A Monthly Donor

Set up an easy, convenient way to make an impact through monthly donations. Plus, receive exclusive benefits each year.

Monthly donations make a significant impact on our organization’s ability to carry out its mission one month at a time.

Donate Annually

Recurring donations provide a stable and reliable source of funding, which is crucial for sustaining our life-changing initiatives.

Join the Three Wish Society with a minimum $2,500 annual contribution and enjoy exclusive donor benefits.

Mail checks and money orders to:
Isabella Santos Foundation
9935-D Rea Road, Unit 275,
Charlotte, NC 28277

EIN: 26-1332748

Mail Checks and Money Orders to:
Isabella Santos Foundation
9935-D Rea Road, Unit 275,
Charlotte, NC 28277

EIN: 26-1332748

Why Support?

At the Isabella Santos Foundation, we know that for families facing rare pediatric cancers, hope is everything. That’s why we’re dedicated to funding innovative research and providing support that gives these brave cancer heroes a fighting chance.

But we can’t do it without you. 

Isabella bravely fought neuroblastoma, a rare and aggressive cancer, for five years before running out of treatment options. Sadly, this is the reality for many children diagnosed with rare cancers.

Pediatric cancer isn’t just one disease—it encompasses 12 major types and over 100 subtypes, making it uniquely complex and vastly underfunded. With little to no government funding, it falls to private foundations like ISF to lead the charge in funding research and developing innovative treatment programs.

When you give to ISF, your support brings hope, healing and a fighting chance to children and families impacted.

More Ways to Give

Donor Advised Funds (DAF) allow you to make a grant from your fund or foundation, serving as a philanthropic vehicle enabling individuals, families or organizations to make charitable contributions, receive an immediate tax deduction and recommend grants to ISF.

Isabella Santos Foundation
9935-D Rea Road, Unit 275,
Charlotte, NC 28277

EIN: 26-1332748

Set up recurring grants from your DAF to help sustain the lifesaving mission of ISF. Contact your fund administrator and choose your preferred grant frequency.

Name ISF as the beneficiary of your DAF to support our mission beyond your own lifetime. Simply contact your fund administrator to do so.

For assistance or questions, contact Dominique Lee.

Gifts of stock are a valuable way to support charitable organizations, and when you donate appreciated stocks or securities to ISF, you receive several benefits:

Tax Deduction: You can generally deduct the full fair market value of the stock as a charitable contribution on your federal income tax return, provided you have owned the stock for more than one year.

Avoid Capital Gains Tax: By donating appreciated stock directly to ISF, you can avoid paying capital gains tax on the appreciation of the stock — this means you can maximize the impact of your donation by giving more to support our mission.

Support a Cause You Care About: Your gift of stock helps ISF continue its lifesaving work in rare pediatric cancer research and treatment, providing hope to children and families facing these devastating diseases.

Make a Gift of Stock.

Commemorate a special milestone with the gift that keeps giving. Dedicate your gift in celebration of a person or any occasion.

Honor giving is a meaningful way to honor or commemorate a special person or event, while supporting a mission that makes a big difference. 

Donating to ISF on behalf of someone means you’re giving back to your community in a charitable way with that person in mind. 

When making your donation, enter the recipient’s information, and we’ll send them a personalized note to notify them of your gift.

Donate by mail. 

Isabella Santos Foundation
9935-D Rea Road, Unit 275,
Charlotte, NC 28277

Honor gifts are tax deductible. 

Make an Honor Gift

Dedicate your gift in honor or memory of a loved one so their legacy lives on.

Memorial donations are gifts to nonprofits in memory of someone. Some families request a memorial donation in lieu of flowers or other tribute gifts to honor the family member who has passed.

Donate online or by mail.

Isabella Santos Foundation
9935-D Rea Road, Unit 275,
Charlotte, NC 28277

Make a Memorial Gift.

______________________

Funeral Resources

Unite and fight for kids with cancer by recommending ISF for future memorials.

Contact ISF for branded envelopes and other memorial resources for the service. Please allow 7-10 business days to receive.

Suggested copy for obituary:

Memorial gifts may be made to the Isabella Santos Foundation, 9935-D Rea Road, Unit 275, Charlotte, NC 28277. Your gift will provide transformational outcomes for rare cancer heroes worldwide.

Memorial donations are tax-deductible.

Planned giving to the Isabella Santos Foundation offers a meaningful way to support our mission of advancing treatments and ensuring a brighter future for rare cancer heroes worldwide.  

By including ISF in your giving plans, you can leave a lasting legacy while achieving your financial goals.

Here’s how to make a planned gift:

  • Bequests: You can include a gift to ISF in your will or living trust. This allows you to designate a specific amount, percentage or asset to support our mission, ensuring that your generosity continues to make a difference for years to come.
  • Charitable Remainder Trusts: By establishing a charitable remainder trust, you can provide income for yourself or your loved ones during your lifetime, with the remaining assets ultimately benefiting children with rare cancer. This can be a tax-efficient way to support our mission while also providing for your family.
  • Gifts of Retirement Assets: Designating ISF as a beneficiary of your retirement account, such as an IRA or 401(k), can significantly support our organization while potentially reducing taxes on your estate.
  • Gifts of Life Insurance: You can name ISF as a beneficiary of your life insurance policy or transfer ownership of a policy to support our mission, allowing donors to make a substantial gift with relatively modest premium payments.
  • Charitable Gift Annuities: By establishing a charitable gift annuity with ISF, you can receive fixed life payments while supporting our work. This option provides financial security for you and your loved ones and the satisfaction of making a meaningful impact.

No matter which planned giving option you choose, your support will help ensure that ISF can continue to provide lifesaving treatments, groundbreaking research and compassionate care to children and families facing the challenges of pediatric cancer and other life-threatening diseases.

Together, we can make a difference in the lives of children worldwide.

To inquire about Legacy Gifts, contact Dominique Lee. 

Amplify your employees’ charitable giving by matching their donations to ISF, doubling the impact of their contributions.

Learn more about our Corporate Champions Program.

Collaborate with ISF on your next event or fundraising campaign to rally the community and your target audience customers around a great cause.

Learn more about Beneficiary Programs.

Become an integral part of our mission, while enjoying exclusive benefits designed to maximize brand awareness and expand your marketing reach, all while making a meaningful impact in the lives of those we serve.

Learn more about Sponsorship Opportunities.